Four other deputies and two civilians were shot by the suspect, who was "no longer a threat", the sheriff's office said on its Twitter account.
A man fired more than 100 rounds at sheriff's deputies early Sunday, killing one and injuring four others, before being fatally shot himself in what authorities called an ambush.
A gunman opened fire, hitting five deputies and two civilians.
Police in Colorado say a number of officers are "down" following a shooting incident outside Denver.More news: Paige Suffers Possible Shoulder Injury During WWE Live Show
The suspect was believed to have been killed, investigators said.
The officers were shot after responding to an initial report of domestic violence at the Copper Canyon Apartments just after 5 a.m., Sheriff Tony Spurlock said in a news conference. It's not known if they are law enforcement.
'A Code Red was sent out regarding this incident.
An emergency shelter was set up at East Ridge Recreation Center at 9568 University Boulevard in Highlands Ranch.
There was no immediate information on the condition of the deputies, the sheriff's office tweeted, saying "the scene remains active".