Arsenal have no players suspended for this game.
Palace boss Roy Hodgson has taken 18 points from 12 games to guide the Eagles to 16th place, just two points above the relegation zone after taking over with the side bottom of the table. Now sat sixth in the table, the Gunners are four points adrift of the top four, they're also three points behind arch-rivals Tottenham.
The Gunners came back from 2-0 down against Liverpool last week to salvage a point with a 3-3 draw.
Arsenal manager Arsene Wenger will equal a Premier League record when he takes the bench for his 810th Premier League game on Thursday.More news: Mahadayi talks only after Karnataka poll: Goa BJP
Arsenal were booed off at Selhurst Park last season as they lost 3-0 and saw their European aspirations dissipate amidst away supporters singing 'You're not fit to wear the shirt'.
And Arsenal make three changes to the side that produced a thrilling 3-3 draw against Liverpool last time out, with Shkodran Mustafi, Sead Kolasinac and Calum Chambers coming in while Ainsley Maitland-Niles, Alex Iwobi and Nacho Monreal drop out. With it becoming increasingly more likely that both Alexis Sanchez and Mesut Ozil will be departing the Emirates next month, Arsenal's need for goals will fall on the shoulders of Alexander Lacazette. With only a single top-flight victory in their last five matches, Arsene Wenger will be traveling to southeast London knowing his Gunners must improve on their recent poor form away from home. The star playmaker has been in impressive form of late and has scored in back-to-back games. However Arsenal this season have only won two games away from home, their joint fewest tally after nine away games in a Premier League season.
The Gunners will, however, be without Aaron Ramsey who is recovering from a hamstring injury.
Then Sanchez, whose future at Arsenal remains uncertain, demonstrated his world-class talent, first with a thunderous 62nd minute snap shot and then a lovely piece of control and fine finish from Jack Wilshere's long, precise through ball.