For Leicester this was vintage Jamie Vardy and Riyad Mahrez while new boy Vicente Iborra was outstanding in their midfield even if they ended up hanging on with Spurs, who missed four clear chances, demanding an injury-time penalty after Danny Rose went down as he shaped to shoot.
Their fast start was soon rewarded with the opening goal inside 12 minutes.
The breakthrough did arrive 13 minutes in, though, with Vardy hooking Marc Albrighton's cross over the head of Lloris on the volley for his seventh goal of the campaign.
The usual suspects were on the scoresheet - for both sides.More news: Record heat on Thanksgiving in Salt Lake City
The Algerian worldwide cut in from the right before curling the ball out of Lloris's reach from 20 yards out.
Mauricio Pochettino and Tottenham now had it all to do in the second half if they harbored hope of returning to north London with anything.
Spurs looked to rally as they pressured the Leicester defense, although Schmeichel and the back four in front of him held firm, resisting the pressure the visitors were beginning to apply, whilst the threat of Vardy and Mahrez the counter still gave Spurs something to think about defensively.
And Spurs should have been level when Serge Aurier flashed a cross to the far post, where Llorente somehow managed to divert the ball over the top from six yards out.
He was soon replaced by Erik Lamela, who instantly made his mark by playing in Kane to rifle a right-foot shot past Schmeichel to halve the deficit.